Method for performing amplification of nucleic acid with two pri

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 6, C12P 1934, C12Q 168

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active

056416580

ABSTRACT:
This invention features methods and apparatus for performing nucleic acid hybridization and amplification processes on a support. Such methods and apparatus are useful for synthesizing nucleic acid and detecting target nucleic acid for diagnostics and therapeutics.

REFERENCES:
patent: 5405746 (1995-04-01), Uhlen
Maskos et al, (1992), "Oligonucleotide hybridizations on glass supports: a novel linker for oligonucleotide synthesis and hybridization properties of oligonucleotides synthesised in situ", Nucleic Acids Res. 20(7):1679-1684.
Stamm et al, (1991), "Sanchored PCR: PCR with cDNA coupled to a solid phase", Nucleic Acids res. 19(6):1350.
Kaneoka et al, (1991), "Solid-phase direct DNA sequencing of allele specific polymerase chain reaction amplified HLA-DR genes", Biotechniques 10(1):30, 32, 34.
Saiki et al, "Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes", Proc. Natl. Acad. Sci. USA 86:6230-6234.

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