Expression of heterologous polypeptides in halobacteria

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 435 711, 435193, 435243, 530350, C12P 2102, C12N 1563, C12N 910, C12N 100

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056416504

ABSTRACT:
This invention relates to the preparation and use of expression systems capable of producing heterologous polypeptides in halobacterial hosts.

REFERENCES:
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Blaseio, U., et al., "Transformation of Halobacterium halobium: Development of vectors and investigation of gas vesicle synthesis", Proc. Natl. Acad. Sci. USA, 87:6772-6776 (1990).
Birge, R.R., "Photophysics and Molecular Electronics Applications of the Rhodopsins", Annu. Rev. Phys. Chem., 41:683-733 (1990).
Betlach, M., et al., "Characterization of a halobacterial gene affecting bacterioopsin gene expression", Nucelic Acids Research, 12:7949-7959 (1984).
Dunn, R., et al., "The bacteriorhodopsin gene", Proc. Natl. Acad. Sci. USA, 78:6744-6748 (1981).
Dunn et al. 1987 J. Biol. Chem, 262, (19) 9246-9254.
Krebs et al. 1991, PNAS, 88:859-863.
Derwent Abstract of Japanese Patent 3151883, Jun. 28, 1991.
Derwent Abstract of Japanese Patent 59036700 Feb. 28, 1984.
The Patent Office Japanese Government "Patent Abstracts of Japan", 8(126):228 (1984).

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