Anti-depressant indole derivatives

Details Anti-depressant indole derivatives Anti-depressant indole derivatives

1978-11-08

1980-06-24

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546201, 546212, 546224, 546273, A61K 31445, C07D40106, C07D40914

Patent

active

042095212

ABSTRACT:
The invention concerns a compound of formula II ##STR1## or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof wherein R.sup.5 represents hydrogen, hydroxy, lower alkoxy or lower alkyl, R.sup.6 represents hydrogen or lower alkyl, and R.sup.7 represents phenyl, lower alkoxy phenyl, halophenyl, or thenyl and X represents oxygen or sulphur. These indole derivatives exhibit psychotropic activity. The invention includes a method of alleviating depression in a warm blooded animal afflicted with depression which method comprises administering to said animal an effective amount of a compound of formula II or a pharmaceutically acceptable acid addition salt thereof.

REFERENCES:
patent: 4061641 (1977-12-01), Archibald et al.
patent: 4073911 (1978-02-01), Huebner

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