Preparation of esters of 2-(6'-methoxy-2'-naphthyl)-propionic ac

Details Preparation of esters of 2-(6'-methoxy-2'-naphthyl)-propionic ac Preparation of esters of 2-(6'-methoxy-2'-naphthyl)-propionic ac

1983-08-04

1985-12-24

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549453, 568591, 568592, C07D31906, C07D31700

Patent

active

045607770

ABSTRACT:
Process for preparing esters of 2-(6'-methoxy-2'-naphtyl)-propionic acid via rearrangement of new ketals of 2-halo-1-(6'-methoxy-2'-naphtyl)-propan-1-one in the presence of a Lewis acid.
The esters thus obtained are useful as intermediate products for preparing Naproxen.
The process involves the preparation of the following new compounds:

REFERENCES:
patent: 2260261 (1941-10-01), Morey
patent: 3626012 (1971-12-01), Fried
patent: 4180585 (1979-12-01), Goudie
patent: 4243682 (1981-01-01), Goudie et al.

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