Substituted aromatic compounds

Details Substituted aromatic compounds Substituted aromatic compounds

1984-03-05

1985-12-24

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544182, 260465E, C07D25306, A61K 3153

Patent

active

045606870

ABSTRACT:
The present invention provides compounds of the formula (III): ##STR1## or an acid addition salt thereof, wherein R.sup.6, R.sup.7, R.sup.9 and R.sup.10 are each hydrogen, halogen, C.sub.1-4 alkyl or trifluoromethyl and R.sup.8 is chlorine or R.sup.7 and R.sup.8 are linked to form a --CH.dbd.CH--CH.dbd.CH-- group when one of R.sup.6 and R.sup.10 is other than hydrogen provided that when R.sup.8 is chlorine R.sup.6, R.sup.7, R.sup.9 and R.sup.10 are not all hydrogen atoms and that any one of R.sup.6, R.sup.7, R.sup.9 and R.sup.10 is not chlorine when the other three groups are hydrogen. Also provided are pharmaceutical compositions containing compounds of the formula (III), the first medical use of compounds of the formula (III), a process for preparing such compounds and intermediates through which this process proceeds.

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