Treatment of diarrhoea with 2-aminoimidazoline derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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548315, 548351, A61K 31415

Patent

active

044501706

ABSTRACT:
Compounds A - B - C wherein A is 2 imidazolinyl or N-alkyl derivative thereof, B is oxygen, sulphur, CR.sup.1 R.sup.2 wherein R.sup.1 and R.sup.2 are hydrogen or alkyl, or NR.sup.3 wherein R.sup.3 is hydrogen or alkyl, and C is a 5 - or 6 - membered carbo- or heterocyclic group having a nitrogen containing substituent and up to two other substituents, are useful in treatment of diarrhoea or scours. Certain compounds A - B - C are novel.

REFERENCES:
patent: 3190802 (1965-06-01), Zeile et al.
patent: 4265900 (1981-05-01), Rasmussen et al.
patent: 4312879 (1982-01-01), Lal
patent: 4332814 (1982-06-01), Newsome et al.
Chemical Abstracts, 94:132312d (1981) [Lal et al., J. Clin. Pharmacol. 1981, 21(1), 16-19].

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