Penicillins and their preparation

Details Penicillins and their preparation Penicillins and their preparation

1975-09-05

1977-01-25

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D49968

Patent

active

040050750

ABSTRACT:
Penicillins of the formula: ##STR1## wherein R is an unsubstituted phenyl group or a substituted phenyl group having one or more hydroxyl groups or a cyclohexadienyl group and A represents a monocyclic or polycyclic nitrogen-containing heterocyclic aromatic ring, which are useful as antimicrobial agents having a broad antimicrobial spectrum against gram-positive and gram-negative bacteria including Pseudomonas and can be produced advantageously from the phenacyl ester of 6-aminopenicillanic acid through a series of steps.

REFERENCES:
patent: 3433784 (1969-03-01), Long et al.
patent: 3741960 (1973-06-01), Alburn et al.
patent: 3804820 (1974-04-01), Quitt et al.
patent: 3864329 (1975-02-01), Tobiki et al.

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