Antiodor, antimicrobial and preservative compositions and method

Drug – bio-affecting and body treating compositions – Anti-perspirants or perspiration deodorants

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514859, 514863, 426531, 426652, 426653, 426654, 426321, 426323, 426335, 252397, 252399, 252404, 252407, A61K 732

Patent

active

056414757

ABSTRACT:
Therapeutic treatment as well as prophylactic measures are provided by topical application of compositions containing an aryl 2-acetoxyethanoic acid to eradicate or prevent the development of axillary foul odor, foot malodor and other body odors, e.g. scalp, and skin, nail and follicular infections caused by microorganisms. The compositions are antimicrobial against several organisms that infect the skin and are specifically effective against P. acnes. The compositions are therapeutically effective against folliculitis and perifolliculitis and are useful for other skin lesions, nail and mucosal infections such as impetigo, seborrheic dermatitis, erythrasma and trichomycosis axillaris, associated with or caused by microorganisms. The therapeutic effect of the composition may be synergized or amplified by incorporating a cosmetic or dermatologic agent into the formulation for topical treatment of cosmetic and dermatologic indications. The compositions are also useful as preservatives in food products, cosmetic and pharmaceutical formulations, and industrial preparations.

REFERENCES:
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patent: 3920835 (1975-11-01), Van Scott et al.
patent: 4105783 (1978-08-01), Yu et al.
patent: 4216224 (1980-08-01), Yu et al.
patent: 4246261 (1981-01-01), Van Scott et al.
patent: 4363815 (1982-12-01), Yu et al.
patent: 4518789 (1985-05-01), Yu et al.
patent: 5258391 (1993-11-01), Van Scott et al.
Current Therapy, p. 662 (1981).
Current Therapy, pp. 599-603 (1984).
The Merck Index, 9th Ed., Abstract 7961 (1976).

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