Novel benzopyran derivatives, processes for their preparation an

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5142268, 5142272, 5142288, 514256, 514275, 514365, 514370, 514374, 514377, 514385, 544 55, 544 96, 544331, 544332, 544333, 548146, 548190, 548193, 548215, 548233, 548234, 548300, 548316, A61K 31425, C07D41304, C07D41704

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active

050969145

ABSTRACT:
Benzopyran derivatives of the general formula I ##STR1## wherein the substituents are as defined herein are provided. The compounds show vasodilating and vascular spasmolytic activity and are useful in treating hypertension.

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J. Med. Chem. 1984, vol. 27, No. 9, pp. 1127-1131, "Synthesis . . . Benzopyran-3-ols", p. 1128.
J. Med. Chem., vol. 29, No. 11, 1986, pp. 2194-2201; "Synthesis . . .-2H-1-benzopyrans", p. 2195.
Chemical Abstracts, vol. 105, 1985, Abstract No. 190938u.
J. Medicinal Chemistry 29, 1986, pp. 2194-2201.
J. Medical Chemistry 27, 1984, pp. 1127-1131.
J. Medicinal Chemistry 26, 1986, pp. 1582-1589.

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