Removal of boronic acid protecting groups by transesterification

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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530326, 530327, 530328, 530329, 530330, 530331, 558288, 558289, 558295, 558298, 558384, 562 7, C07D20714, C07F 502, C07F 504

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active

053844106

ABSTRACT:
A method for the removal of ester protecting groups from .alpha.-amino boronic acid is disclosed for the preparation of compounds of formula (II) below

REFERENCES:
patent: 4499082 (1985-02-01), Shenvi et al.
patent: 4537773 (1985-08-01), Shenvi
Gross & Meienhofer; "The Peptides, Analysis, Synthesis, Biology"; vol. 3, (1981), pp. 1 to 98 and 341 to 448; Academic Press, N.Y.
Kettner and Shenvi, The Journal of Biological Chemistry 259; pp. 15106-15112, (1984).
Matteson, Chemistry Review 89; (1989), pp. 1535-1551.

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