High molecular mass N,O-sulphated heparosans, process for their

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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514 56, C12P 1904, C12N 120

Patent

active

053843983

ABSTRACT:
The subject of the invention is new high molecular mass N,O-sulphated heparosans consisting of chains or of a mixture of chains having a molecular mass of between 1.5.times.10.sup.4 and 4.0.times.10.sup.6 D, characterized by a repeating disaccharide structure of formula I: ##STR1## in which E represents, in 0 to 80% of the disaccharide units of the said N,O-sulphated heparosan, an acetyl group and, in the remaining disaccharide units, a sulphate group and optionally a hydrogen atom, G represents a hydrogen atom and a sulphate group, and the pharmaceutically acceptable salts of the said N,O-sulphated heparosans.

REFERENCES:
patent: 5314876 (1994-05-01), Lormeau et al.

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