Substituted thiophene-2-sulfonamide antiglaucoma agents

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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514315, 514326, 514351, 514396, 514401, 514408, 514445, 544146, 544379, 546184, 546284, 546347, 548327, 549 60, 549 61, 549 66, C07D33322, C07D24104, C07D26530

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active

047217944

ABSTRACT:
Thiophene-2-sulfonamides with a 5-alkyl-S(O).sub.n -substituent are carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure.

REFERENCES:
Barnish et al., C.A., vol. 90, 1979, 90:54813u, p. 598.
Cross et al., C.A., vol. 87, 1977, 87:84803w, p. 579

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