Azetidine-3-carboxylic acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20504

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active

047217936

ABSTRACT:
The novel ester, N-benzylazetidine-3-carboxylic acid methyl ester and its use in the preparation of the corresponding free acid by a process which comprises reacting N-benzyl-3-cyanozetidine with methanol and hydrolyzing the resulting methyl ester with hot water.

REFERENCES:
K. Kumoto et al., Chem. Abstracts, vol. 89 (1978), entry 197344g.
March, ed., Advanced Organic Chemistry, 2nd ed., McGraw-Hill (1977), pp. 809-810 and 813-814.
Sandler et al., Organic Functional Group Preparations, vol. III, Academic Press (1972), pp. 268-273.
Spiegel, Chem. Berichte, vol. 51 (1918), pp. 296-298.

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