Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1985-09-23
1988-01-26
Foelak, Morton
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530387, 530412, 530418, 530427, 424 85, 424101, C07K 312
Patent
active
047217774
ABSTRACT:
Virus-contaminated immunoglobulin can be virus-inactivated by heating it in a substantially dry state at a temperature of 30.degree. to 100.degree. C. for a period of time sufficient for inactivating virus with maintaining original activity of the immunoglobulin. The addition of glycine, sodium chloride, sodium acetate, polyethylene glycol, albumin or mannitol enhances the effect and gives good solubility and good state to the solution of the virus-inactivated immunoglobulin.
REFERENCES:
patent: 4327086 (1982-04-01), Fukushima et al.
patent: 4440679 (1984-04-01), Fernandes et al.
patent: 4446134 (1984-05-01), Naito et al.
patent: 4590002 (1986-05-01), Zalton et al.
Rahn, Physical Methods of Sterilization of Microrganisms, pp. 1-36.
Funayama Masahiro
Goto Takashi
Nishida Masayuki
Suyama Tadakazu
Takahashi Tsuyoshi
Draper Garnette D.
Foelak Morton
The Green Cross Corporation
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