Chemistry: analytical and immunological testing – Biospecific ligand binding assay – Utilizing isolate of tissue or organ as binding agent
Patent
1982-01-12
1984-12-11
Padgett, Benjamin R.
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
Utilizing isolate of tissue or organ as binding agent
548542, 548545, 260349, G01N 3358, C07C11700, G01N 2175, G01N 3360
Patent
active
044878389
ABSTRACT:
A crosslinking reagent consisting of a first functional group capable of forming a covalent derivative with a material of interest; a second functional group capable of forming an in situ bond to a neighboring material upon activation; a cleavable bond separating said first and second groups; and a radioactive marker to identify the neighboring material after cleavage of said bond, whereby in situ protein interactions can be studied.
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Hynes Richard O.
Schwartz Martin A.
Engellenner Thomas J.
Massachusetts Institute of Technology
Moskowitz M.
Padgett Benjamin R.
Smith, Jr. Arthur A.
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