Method for augmenting fetal hemoglobin

Details Method for augmenting fetal hemoglobin Method for augmenting fetal hemoglobin

1990-05-04

1991-06-18

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514517, 514546, 514551, 514557, 514561, 514578, 514815, A61K 3119, A61K 3141, A61K 31255

Patent

active

050250299

ABSTRACT:
A method is provided for inhibiting the .gamma. to .beta.-globin switching in subjects afflicted with .beta.-globin disorders. The method is particularly adapted for ameliorating the clinical symptoms of sickle cell anemia by periodically introducing butyrate, or certain isomers, homologs, analogs or chemical variations thereof, into the bloodstream of the subject prior to natural completion of the switching process.

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