Fluorinated methyl beta-alanine derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424305, 424320, 560 39, 560 41, 560161, 560190, 560192, 560227, 560172, 562448, 562449, 562561, 564197, 564198, 564509, C07C10110, A61K 31195

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active

043754775

ABSTRACT:
Beta-monofluoromethyl beta-alanine, beta-difluoromethyl beta-alanine and pharmaceutically acceptable esters and amides derived from the acid group, amides derived from the amine group, and salts thereof are novel compounds which inhibit .gamma.-aminobutyric acid transaminase (GABA-T).

REFERENCES:
patent: 4264590 (1981-04-01), Chu

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