Process for the preparation of 6-hydroxymethyl-2-(.beta.-aminoet

Details Process for the preparation of 6-hydroxymethyl-2-(.beta.-aminoet Process for the preparation of 6-hydroxymethyl-2-(.beta.-aminoet

1980-09-12

1983-03-01

Lee, Mary C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

548513, 548533, 204158R, 560119, C07D48704

Patent

active

043754333

ABSTRACT:
Disclosed is a process for preparing the antibiotic 6-hydroxymethyl-2-(.beta.-aminoethylthio)-1-carbadethiapen-2-em-3-carboxyl ic acid (I) ##STR1## and its pharmaceutically acceptable salt and ester derivatives. An intermediate for the production of these compounds are compounds of the formula ##STR2## wherein R.sup.5 and R are readily removable protecting groups.

REFERENCES:
patent: 4252722 (1981-02-01), Melillo et al.

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