Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1980-09-12
1983-03-01
Lee, Mary C.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
548513, 548533, 204158R, 560119, C07D48704
Patent
active
043754333
ABSTRACT:
Disclosed is a process for preparing the antibiotic 6-hydroxymethyl-2-(.beta.-aminoethylthio)-1-carbadethiapen-2-em-3-carboxyl ic acid (I) ##STR1## and its pharmaceutically acceptable salt and ester derivatives. An intermediate for the production of these compounds are compounds of the formula ##STR2## wherein R.sup.5 and R are readily removable protecting groups.
REFERENCES:
patent: 4252722 (1981-02-01), Melillo et al.
Melillo David G.
Ryan Kenneth M.
Arno James A.
Lee Mary C.
Merck & Co. , Inc.
Pfeiffer Hesna J.
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