Chemical modification of repetitive polymers to enhance water so

Details Chemical modification of repetitive polymers to enhance water so Chemical modification of repetitive polymers to enhance water so

1994-11-21

1998-06-02

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530353, C07K 14195

Patent

active

057600040

ABSTRACT:
Highly repetitive proteins which are relatively insoluble in water are chemically modified to increase solubility. The protein is reacted with a functionalizing agent to introduce additional polar functionalities and disrupt the order of the protein. The solubility of the protein in water is increased by the chemical modification, while adhesive and surfactant properties are retained.

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Sakamoto et al., Gas Limomatography of Chemistry Modified Amino Acids in Silk & WooL Meard with Alkylene Oxides CAPLUS #1983:523944, 1983.
Topchieva, "Protein Adducts with Water Soluble Poly Alkylene Oxides" (1995), Chem Abs #124:15319.
Topchieva, "Conjugates of Proteins w/Propylene Oxides" (1994), Chem Abs #123:308720.
Allemand, "Cosmetics Based on Estemified Proteins" (Aug. 13, 1971), Chem Abs #77:24780.
Kyowa, "Hydroxyalkylaneo Proteins" (Sep. 19, 1969), Chem Abs #72:67273.

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