Derivatives of 2, 3, 6-trifluorophenols and a process for their

Details Derivatives of 2, 3, 6-trifluorophenols and a process for their Derivatives of 2, 3, 6-trifluorophenols and a process for their

1996-12-11

1998-12-15

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568631, 568635, 568656, 568731, 568774, 568775, 568776, C07C 4100

Patent

active

058499598

ABSTRACT:
The present invention relates to compounds of the formula (1) ##STR1## where R is H, a straight-chain or branched alkyl radical with 1 to 6 carbons, a fluorinated straight-chain or branched alkyl radical with 1 to 6 carbons, a benzyl radical, or a benzyl radical substituted by an alkyl group or alkoxy group with 1 to 4 carbons each, or by halogen, X is H, Cl, Br or I, and X is different from R, and a process for their preparation.

REFERENCES:
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patent: 5446198 (1995-08-01), Pfirmann et al.
patent: 5525258 (1996-06-01), Wingen et al.
(Abstract) Ramanan et al., Indian Drugs (1985), 23(2), 105-107, 1985.
Burdon, "Aromatic Polyfluoro-Compounds. Part XVI", J, J. Chem. Soc., London, pp. 6326-6328 (Nov. 1965).
Wray, Victor et al., "Additivity of Substituent Effects Upon Proton-Fluorine Coupling Constants in Polysubstituted Fluorobenzenes", J. Chem. Cos. Perkin II, London, pp. 1307-1312, (1976).
March, J.: Advanced Organic Chemistry, fourth edition, 1992, pp. 563-565.
Greene, T., "Aromatic Ethers", Chapter 3, Protective Groups in Organic Chemistry, N.Y., John Wiley and Sons, 1991, pp. 143-174.

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