Nucleic acid molecule encoding ciliary neurotrophic factor recep

Details Nucleic acid molecule encoding ciliary neurotrophic factor recep Nucleic acid molecule encoding ciliary neurotrophic factor recep

1995-05-19

1998-12-15

Teng, Sally P.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 691, 435325, 4352523, 4352542, 435348, 4353201, 530350, C12N 1512, C07K 14705

Patent

active

058498974

ABSTRACT:
The present invention relates to the ciliary neurotrophic factor (CNTF) receptor, and provides for CNTF receptor nucleic acid and amino acid sequences. It also relates to (i) assay systems for detecting CNTF activity; (ii) experimental model systems for studying the physiologic role of CNTF; (ii) diagnostic techniques for identifying CNTF-related neurologic conditions; (iv) therapeutic techniques for the treatment of CNTF-related neurologic and muscular conditions, and (v) methods for identifying molecules homologous to CNTF and CNTFR.

REFERENCES:
Yamasaki et al., Science, 241, 825, 1988.
Wallace et al., Methods in Enzymology, 152, 432 1987.
Davis et al., Science, 253, 59, 1991.
Ip et al., Neuron, 10, 89-102, 1993.

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