Substituted indole-2-carboxylic acids as glucosyl transferase in

Details Substituted indole-2-carboxylic acids as glucosyl transferase in Substituted indole-2-carboxylic acids as glucosyl transferase in

1998-07-28

1999-11-09

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20912

Patent

active

059817623

ABSTRACT:
Indole carboxylic acids are useful as UGGTASE inhibitors.

REFERENCES:
Avromenko et al., "Indole Derivatives. LIV. Synthesis of 3,5-Diacetylindole." Chem. Heterocycl. Compd., vol. 6 (1970), p. 1131.
Ruhemann, S; Blackman, F., "LX. Benzophenylhydrazine." J. Chem. Soc., vol. 55 (1889), p. 617.
Chem. Pharm. Bull. 38(12) 3261-3267 (1990), Masanobu Tani etal.: "Synthetic Studies on Indoles and Related Compounds. XXV. The Friedel-Crafts Acylation of Ethyl 1H-Indole-2-carboxylate. "
Database Xfire Beilstein Reg. No. 384515 XP002079476.
Warner-Lambert Research Institute, Morris Plains, New Jersey, Maximillan Von Strandtmann, et al.: "Acltryptamines III. 5-Acetyltryptophan and Related Compounds. "
Biochemistry, 1989, 28, 8108-8116, "Glucosylation of Glycoproteins by Mammalian, Plant, Fungal, and Trypanosomatid Protozoa Microsomal Membranes ".

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