Method of treating menopause or perimenopause

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514176, A61K 3158

Patent

active

059815167

ABSTRACT:
A method of treating cholesterol without estrogenic activity at the uterine level in women comprising administering to women an amount of a steroid of the formula ##STR1## wherein the substituents are defined as in the specification without estrogenic activity at the uterine level.

REFERENCES:
patent: 4978657 (1990-12-01), Teutsch et al.
Qian et al, "Synthesis. . . Antiestrogens", Steroids, vol. 55, No. 5, May 1990, pp. 238-241.
Cvrtila et al, "Estrogen. . . Breast Cancer", Period. Biol., vol. 88, No. 3, 1986 pp. 253-260.
Gottardis et al, "Effect. . . Athymic Mice", Cancer Research, vol. 50, No. 11, 1990 pp. 3189-3192.
Gottardis et al, "Inhibition. . . Antiestrogens", Cancer Res., vol. 49, No. 15, 1989, pp. 4090-4093

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