Peptidyl compounds

Details Peptidyl compounds Peptidyl compounds

1996-10-04

1999-11-09

Celsa, Bennett

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 514389, 530331, 564153, 564154, 5483014, 4241841, 4241851, A61K 3805, C07K 500

Patent

active

059814900

ABSTRACT:
Dipeptide compounds have therapeutic utility, inter alia, as metalloproteinase and TNF inhibitors.

REFERENCES:
Miller, R.B. et al. (1985) "Incorporation of Coordinating Amide Bond Surrogates within Mammalian Collagenase Inhibitors" Pept. Struct. Funct., Proc. Am. Pept. Symp., 9th:815-818.
Gray, R.D. et al. (1981) "Metal Binding Peptide Inhibitors of Vertebrate Collagenase" Biochemical and Biophysical Research Communication 101(4):1251-1258.
Fournie-Zaluski et al., Eur. J. Biochem 139 267-74(1984).
Spatola et al, "Chemistry & Biochemistry --Proteins" vol. 7 (Marcell Dekkes, 1983, Weinstein Ed) pp. 267-268, 338-340.

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