Method of treating colon, renal, and lung carcinomas with

Details Method of treating colon, renal, and lung carcinomas with Method of treating colon, renal, and lung carcinomas with

1993-12-23

1998-12-15

Carlson, Karen Cochrane

Drug, bio-affecting and body treating compositions

Lymphokine

424 852, 424 854, 424 855, 530351, A61K 4505, A61K 3766, C07K 14545, C07K 1457

Patent

active

058492828

ABSTRACT:
This invention provides an anti-tumor agent and a method for treating a tumor wherein gamma-interferon and interleukin-1 are used as active ingredients.

REFERENCES:
patent: 4898818 (1990-02-01), Nakai et al.
patent: 5145667 (1992-09-01), von Eichborn et al.
patent: 5145677 (1992-09-01), von Eichborn et al.
Momparler, "In vitro Systems for Evaluation of Combination Chemotherapy", Pharmac. Ther., 8:21-35 (1980).
Dempsey et al, "The Differential Effects of Human Leukocytic Pyrogen/Lymphocyte-Activating Factor, T Cell Growth Factor, and Interferon on Human Natural Killer Activity", J. Immuno., 129(6):2504-2510 (1982).
Tsai et al, "Modulation of Cell Proliferation by Human Recombinant Interleukin-1 and Immune Interferon", J.N.C.I., 79(1):77-81 (1987).
Chen et al, "Interferon-.gamma. Synergizes with Tumor Necrosis Factor and with Interleukin 1 and Requires the Presence of Both Monokines to Induce Antitumor Cytotoxic Activity in Macrophages", J. Immuno., 139(12):4096-4101 (1987).
Hashimoto et al, "Role of Culture Supernatant of Cytotoxic/Cytostatic Macrophages in Activation of Murine Resident Peritoneal Macrophages", Canc. Immuno. Immunotherapy, 28(4):253-259 (1989).
Sodhi et al, "Activation of Murine Macrophages by Tumor Necrosis Factor, Interleukin-1, Interferon-.gamma. and Cisplatin", Immuno. Letters, 26(1):45-50 (1990).
Kurtz et al, "Separate and Combined Effects of Recombinant Interleukin-1.alpha. and Gamma Interferon on Antibacterial Resistance", Infect. Immuno., 57(2):553-558 (1989).
Kamogashira et al. 1988. Biochem Biophys Res. Commun. 150(3): 1106-1114.
Wheelock, Science, 149:310-311 (1965).
Falcoff, J. Gen. Virol., 16:251-253 (1972).
Yip et al, Science, 215:411-413 (1982).
Crane et al, J. Nat'l Cancer Inst., 61:871-874 (1978).
Blalock et al, Cell Immunol., 49:390-394 (1980).
Mizel, Immunol. Rev., 63:51-71 (1982).
Dinarello, New Engl. J. Med., 311:1413-1418 (1984).
Falkoff et al, J. Immunol., 131:801=805 (1983).
Onozaki et al, J. Immunol., 135:3962-3968 (1985).
Romano et al, Proc. ACCR, 27:316 (1986).
Perez et al, Proc. ASCO, 5:234 (1986).
Nathan et al, Nature, 292:842-843 (1981).
Matsuyama et al, J. Immunol., 129:450-451 (1982).
Gray et al, Nature, 295:503-508 (1982).
Rinderknecht et al, J. Biol. Chem., 259:6790-6797 (1984).
Semple et al, Cancer Res., 38:1345-1355 (1978).
Moore et al, J. Am. Med. Assoc., 199:519-524 (1967).
Leibovitz et al, Cancer Res., 36:4562-4569 (1976).
Leibovitz, Am. J. Hyg., 78:173-180 (1963).
Fogh et al, J. Nat'l Cancer Inst., 58:209-214 (1977).
Eagle, Science, 130:432-437 (1959).
North et al. 1988 J. Exp. Med. 168 : 2031.
Krigel et al 1987. AAOHN J. 35(4) : 159.
Onozaki et al 1985 J. Immunol 135(6): 3962.

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