Chromium polynicotinate compositions and uses thereof

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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514188, 514570, A61K 3578, A61K 31555, A61K 3119

Patent

active

059809051

ABSTRACT:
Compositions comprising chromic tripicolinate or chromic polynicotinate in combination with at least one of a cyclooxygenase inhibitor, an acid, a mucolytic and a salicin-containing herb. The compositions are useful for supplementing dietary chromium, lowering blood glucose levels, lowering serum lipid levels and increasing lean body mass.

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patent: 5087623 (1992-02-01), Boynton et al.
patent: 5087624 (1992-02-01), Boynton et al.
patent: 5175156 (1992-12-01), Boynton et al.
patent: 5194615 (1993-03-01), Jensen
Boyle, et al., Chromium Depletion n the Pathogenesis of Diabetes and Atherosclerosis, Southern Medical Journal 70(12):1449-1453, 1977.
Carstensen,, J.T., Pharmaceutical Principles of Solid Dosage Forms, Technonic Publishing Co., Inc., Lancaster, PA, pp. 228-230, 1993.
Kamath, et al., Absorption, Retention and Urinary Excretion of Chromium-51 in Rats Pretreated with Indomethacin and Dosed with Dimethylprostaglandin E.sub.s, Misoprostol or Prostacyclin .sup.1,2,3, J. Nutrition 127:478-482, 1997.
Singh, et al., Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non-steroidal anti-flammatory agent, Agents and Actions 18:407-412, 1986.
Coated Pharmaceutical Dosage Forms: Fundamentals, Manufacturing Techniques, Biopharmaceutical Aspects, Test Methods and Raw Materials, CRC Press, Washington, DC, 1998.
Recommended Daily Allowances, Ninth Revised Edition, The national Academy of Sciences, p. 160, 1980.

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