Hydroxamic acid based collagenase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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Details

2605005H, C07C 8310, A61K 31085, A61K 31165, A61K 31185

Patent

active

045993610

ABSTRACT:
This disclosure relates to a novel class of hydroxamic acid based collagenase inhibitor derivatives. The disclosure further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions in the treatment of collagenase induced diseases.

REFERENCES:
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patent: 4028401 (1977-06-01), Fessler et al.
patent: 4077998 (1978-03-01), Fessler et al.
patent: 4105789 (1978-08-01), Ondetti et al.
patent: 4397867 (1983-08-01), Blake
patent: 4419365 (1983-12-01), McLachlan

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