Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-10-17
1999-01-26
Jarvis, William R. A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31415
Patent
active
058639349
ABSTRACT:
Disclosed is a method of treating disorders which have prominent symptoms of behavioral disinhibition (e.g., Attention-Deficit Hyperactivity Disorder, Conduct Disorder, Oppositional Defiant Disorder, Tourette's Syndrome, Lesch-Nyhan Syndrome, or the disinhibitory symptoms accompanying Post-traumatic Stress Disorder or dementia) in a primate with minimal sedative side effects by administering thereto a therapeutically effective amount of lofexidine.
REFERENCES:
patent: 4404226 (1983-09-01), Matejcek et al.
Hunt et al, J. Amer. Acad. Child Psych., vol. 24, pp. 617-629, 1985.
Chappell et al, Derwent Drug File Abstracts, abstract No. 95-27904, 1994
Kunchandy et al, Chemical Abstracts, vol. 105, No. 23, abstract No. 203125d, 1986.
Arnsten Amy F. T.
Goldman-Rakic Patricia S.
Hunt Robert D.
Arnsten Amy F. T.
Goldman-Rakic Patricia S.
Hunt Robert H.
Jarvis William R. A.
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