Hydroxybiotin

Details Hydroxybiotin Hydroxybiotin

1975-09-05

1977-10-18

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

2603322A, 260455B, 260534E, 260561N, 560 12, 560 13, 560 16, 560153, 560156, C07D49504

Patent

active

040547400

ABSTRACT:
This invention relates to a synthesis of biotin by the reduction of dehydrobiotin. The dehydrobiotin is prepared from 6-hydroxy-7-nitro-heptanoic acid methyl ester. Novel intermediates are also obtained by this synthesis.

REFERENCES:
patent: 2436851 (1948-03-01), Businger
patent: 2489234 (1949-11-01), Goldberg et al.
patent: 2489236 (1949-11-01), Goldberg et al.
patent: 3740416 (1973-06-01), Gerecke et al.
Safir et al., J. Org. Chem., 1947, vol. 12, pp. 475-482.

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