Isoindolin-1-one derivatives

Details Isoindolin-1-one derivatives Isoindolin-1-one derivatives

1976-03-23

1977-10-18

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260250AH, 260268H, 26029367, 2603261, 544114, 544131, 544144, 544142, A61K 3150, C07D40312

Patent

active

040546543

ABSTRACT:
Isoindolin-1-one derivatives substituted on the nitrogen atom in the 2-position by an unsubstituted or substituted phenyl radical or a heterocyclic radical having aromatic characteristics, substituted in the 3-position by a 3-amino(or substituted amino)-2-hydroxy-propoxy group, and optionally substituted in the 5- and/or 6-positions by one or two alkoxy radicals or optionally substituted in the 5- and 6-positions by a methylenedioxy radical, possess pharmacodynamic properties, and are especially useful as antiarrhythmic agents.

REFERENCES:
S.U.C.R.P. Chem. Abs. 82, 156062a (1975).
Cotrel et al., I, Chem. Abs. 79, 146393h (1973).
Cotrel et al., II, Chem. Abs. 78, 72197c (1973).

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