Platinum complexes of antitumor agents

Details Platinum complexes of antitumor agents Platinum complexes of antitumor agents

1983-07-29

1985-10-01

Sneed, Helen M. S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

546112, 548109, 549 3, 549206, 556137, 556 32, C07F 1500, A01N 5502, A61K 3128

Patent

active

045447594

ABSTRACT:
The compounds are the class of substituted hydrazine carboximidamides which are useful for inducing the regression and/or palliation of leukemia and related cancers in mammals when administered in amounts of from about one mg. to about 1.2 gm. per square meter of body surface area per day.

REFERENCES:
patent: 3892790 (1975-07-01), Tobe et al.
patent: 3904663 (1975-09-01), Tobe et al.
Connors et al, Platinum Coordination Complexes in Cancer Chemotherapy, Springer Verlag, N.Y., pp. 34 & 35, (1974).
Chemical Abstracts 79, 26649z, (1973).
Chemical Abstracts 96, 134801c, (1982).
Chemical Abstracts 91, 116501z, (1979).
Chemical Abstracts 93, 230058z, (1980).

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