Thiadiazole derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548203, 548204, 548134, 548136, 544 26, 544 27, C07D28506, C07D28512, A61K 31425

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active

045447519

ABSTRACT:
3,7-disubstituted-3-cephem-4-carboxylic acid compounds having bacteriostatic properties and the following formula: ##STR1## in which R.sup.1 is thiadiazolyl or isothiazolyl, each of which may have suitable substituent(s), or thiazolyl; R.sup.2 is hydrogen or lower alkyl; R.sup.3 is carboxy or protected carboxy; R.sup.4 is hydrogen, acyloxy or a heterocyclicthio group which may have suitable substituent(s); and R.sup.5 is hydrogen or lower alkoxy, process for making same and treating infectious diseases therewith.

REFERENCES:
patent: 3971778 (1976-07-01), Cook et al.
patent: 4331665 (1982-05-01), Teraji
patent: 4332798 (1982-06-01), Teraji et al.

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