Cyanobenzano[b]pyrans

Details Cyanobenzano[b]pyrans Cyanobenzano[b]pyrans

1980-10-17

1983-07-05

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

424278, 424267, 546196, 548525, 549399, A61K 31395, C07D40504

Patent

active

043918158

ABSTRACT:
2,2-Dimethyl-3,4-dihydro-2H-benzo[b]pyran-3-ols bearing an amino group in the 4-position and a cyano group in the benzo ring, their salts, esters and ethers, demonstrate excellent vasodilatory activity. The compounds, of which trans-2,2-dimethyl-4-isopropylamino-6-cyano-3,4-dihydro-2H-benzo[b]pyran-3 -ol is a representative embodiment, can be prepared from the corresponding 3,4-epoxy derivative upon treatment with an amine.

REFERENCES:
patent: 4048317 (1977-09-01), Watts

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