Method for producing L-lysine by fermentation

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435 68, 435172, 435253, 435317, 435849, C12P 1308, C12N 1500, C12N 120, C12N 100

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043461700

ABSTRACT:
An L-lysine producing microorganism which is obtained by incorporation into a host strain of the genus Escherichia of a hybrid plasmid having inserted therein a DNA fragment with genetic information controlling L-lysine production which is derived from a donor strain which is resistant to an L-lysine analogue, is useful for the production of high levels of L-lysine by fermentation.

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patent: 4169763 (1979-10-01), Nakayama et al.
patent: 4237224 (1980-12-01), Cohen et al.
patent: 4278765 (1981-07-01), Debabov et al.
Shive et al., in Metabolic Inhibitors, A comprehensive Treatise, (1963), Hochster et al. (ed.), Academic Press, New York, vol. 1, pp. 1-4, 22-23.

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