Chemistry: analytical and immunological testing – Automated chemical analysis
Patent
1985-09-26
1988-04-12
Marcus, Michael S.
Chemistry: analytical and immunological testing
Automated chemical analysis
422 67, 422 73, 422 68, 358213, 436164, 436805, 436807, G01N 2100
Patent
active
047374640
ABSTRACT:
An apparatus for determining a characteristic of a signal modulating component related to an analyte of interest at an assay site by measuring light modulated by the component. A light source uniformly illuminates the assay site and a reference site. The light is directed from the sites onto a group of memory cells on the surface of a random access memory. The memory cells will decay from a logical 1 to a logical 0 due to the light over a period of time which is a function of the intensity of the light and the reference voltage of the memory cells marking the difference between a 1 and a 0. The digital state of each of the memory cells in the group is measured a predetermined exposure time. The measured states of a group of memory cells corresponding to the assay site are compared to the memory cell states for a reference group. The measured states are then analyzed to determine a characteristic of the analyte.
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Briggs Jonathan
McConnell Harden M.
Parce John W.
Caserza Steven F.
Marcus Michael S.
Molecular Devices Corporation
Rowland Bertram I.
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