Antidepressant imidazolines and related compounds

Details Antidepressant imidazolines and related compounds Antidepressant imidazolines and related compounds

1983-03-14

1985-09-10

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514396, 514400, 544242, 544335, 548335, 548355, A61K 31415, C07D23306, C07D23358

Patent

active

045407053

ABSTRACT:
2-(2-Naphthalenyl)alkyl-4,5-dihydro-1H-imidazoles and -tetrahydropyrimidines, the corresponding 3,4-dihydronaphthalenyl and 1,2,3,4-tetrahydronaphthalenyl compounds; and the corresponding indene and indane derivatives, useful as antidepressant or diuretic agents, are prepared by reacting the appropriate 2-(cyanoalkyl)naphthalene or -indane derivative (or the corresponding ester or imino-ether) with an alkylenediamine.

REFERENCES:
patent: 2161938 (1939-06-01), Sonn
patent: 2731471 (1956-01-01), Synerholm et al.
patent: 3354175 (1967-11-01), Fruhstorfer et al.
Izquierdo, I., et al., Revista Farmaceutica 97, 196-197, (1955).

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