Simultaneous calibration heterogeneous immunoassay

Details Simultaneous calibration heterogeneous immunoassay Simultaneous calibration heterogeneous immunoassay

1982-07-16

1985-09-10

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435188, 436524, 436525, 436527, 436529, 436531, 436824, G01N 3354, C12N 996

Patent

active

045406596

ABSTRACT:
An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) comprising ligand and receptor. By providing a first measurement surface capable of specifically binding a labelled reagent in an amount depending upon the presence of analyte in the sample and a second calibration surface capable of binding a second labeled reagent in a manner unaffected by the presence of analyte in the sample, calibration of individual tests can be accomplished simultaneously with the performance of the test itself. A signal producing system includes an enzyme, a catalyst usually bonded to a mip which defines the first labeled reagent for binding to the measurement surface and the same catalyst conjugated to a ligand capable of binding to the calibration surface. Preferably, both labeled reagents have the same composition and the calibration surface includes anti-(first catalyst).

REFERENCES:
patent: 4294817 (1981-10-01), Burgett
patent: 4315907 (1982-02-01), Fridlender et al.
patent: 4331650 (1982-05-01), Brewer et al.
patent: 4366241 (1982-12-01), Tom et al.

Affiliated with

Also associated with

Rating

Simultaneous calibration heterogeneous immunoassay does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Simultaneous calibration heterogeneous immunoassay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Simultaneous calibration heterogeneous immunoassay will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1428559