2-[(R) Amino acid alkyl]penems

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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2602452R, C07D49900, A61K 31425

Patent

active

045405794

ABSTRACT:
Disclosed are 6-(1'-hydroxyethyl)-2-[(R)-amino acid alkyl]penem-3-carboxylic acids and salts thereof having an absolute stereochemisty of 5R,6S,8R. The compounds are useful and potent antibacterial agents and can be formulated into a variety of forms suitable for oral, parenteral or topical use.

REFERENCES:
patent: 4260618 (1981-04-01), Christensen et al.
patent: 4272437 (1981-06-01), Menard et al.
patent: 4301074 (1981-11-01), Christensen et al.
patent: 4431658 (1981-02-01), Afonso
patent: 4448782 (1984-05-01), Afonso

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