Modified phenylalanine peptidylaminodiols

Details Modified phenylalanine peptidylaminodiols Modified phenylalanine peptidylaminodiols

1986-01-16

1987-07-14

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530331, 546146, 546141, 540476, 540593, 540451, 540523, 564153, 564157, A61K 3702, C07K 508, C07D21722, C07D21700, C07C10300, C07C10320

Patent

active

046802843

ABSTRACT:
The invention relates to renin inhibiting compounds of the formula: ##STR1## wherein R.sub.2 is loweralkyl or arylalkyl; R.sub.3 is loweralkyl; X is ##STR2## wherein A is hydrogen or an N-protecting group, R.sub.1 is loweralkyl or arylalkyl, m is 1-3, n is 1-3, p is 1-3, q is 1-3, s is 1-3, and t is 0-2.

REFERENCES:
patent: 4548926 (1985-10-01), Matsueda et al.
Chem. Abstr., vol. 102, (1985), 91909.
Chem. Abstr., vol. 93, (1980), 205010.
Chem. Abstr., vol. 99, (1983), 122958.

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