Therapeutic agent for dermatosis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514844, 514846, A01N 4316

Patent

active

058542795

ABSTRACT:
The present invention provides a therapeutic agent for fundamentally preventing, treating or ameliorating dermatosis, such as, non-infectious dermatosis, which include psoriasis and atopic dermatitis. The therapeutic agent comprises a glycerol derivative represented by the formula (I): ##STR1## wherein A is a group represented by the formula: ##STR2## or single bond; R.sup.1 is a group represented by the formula: ##STR3## wherein R.sup.2 is a methoxyphenyl group or methyl group, X is an atom or atomic group which may become an anion
or a group represented by the formula: ##STR4## or a pharmacologically acceptable salt thereof as an active ingredient.

REFERENCES:
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Inagaki et al., J. Pharmacobio-Dyn., 13, 272-277 (1990).
Hayashi et al., Japan. J. Pharmacol., 44, 127-134 (1987).
Woodward et al., J. Pharmacology and Experimental Therapeutics, 272 (2) 758-765 (Feb. 1995).
Tsushima, et al; "Chem. Pharm. Bull." 32 (7), 2700-2713 (1984) ; Synthesis and Biological Activities of N-Alkyl- and N-Alkenylcarbamoyl Phospholipids .

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