Polyesters containing alkylene oxide blocks as drug delivery sys

Details Polyesters containing alkylene oxide blocks as drug delivery sys Polyesters containing alkylene oxide blocks as drug delivery sys

1986-09-05

1989-11-21

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424 78, 525415, 528354, A61K 3174, C08G 6308

Patent

active

048821683

ABSTRACT:
The invention is a slow release drug delivery system comprising a drug and an ABA or AB block copolymer wherein one block (B) is a poly(alkylene oxide) and the other blocks (A) are comprised of degradable random copolymers of (1) the cyclic ester of an alpha-hydroxy acid and (2) a second cyclic ester monomer is with the proviso that the second cyclic ester monomer not the same as the first cyclic ester.

REFERENCES:
patent: 4300565 (1981-11-01), Rosensaft et al.
patent: 4429080 (1984-01-01), Casey et al.
patent: 4526938 (1985-07-01), Churchill et al.
patent: 4716203 (1987-12-01), Casey et al.

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