Preparation of cis-isoambrettolides and their use as a fragrance

Details Preparation of cis-isoambrettolides and their use as a fragrance Preparation of cis-isoambrettolides and their use as a fragrance

1996-07-09

1998-03-10

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

560260, C07D31500

Patent

active

057263280

ABSTRACT:
A method for the production of .omega.-haloalkyl esters which are useful as intermediates in the synthesis of cis-oxacycloheptadec-11-en-2-one (Product I) and cis-oxacycloheptadec-12-en-2-one (Product II). Also disclosed is a process for the synthesis of Products I-II and a method for using Products I-II to impart an ambery or musky smell to a fragrance composition. Finally, fragrance compositions including Products I-II are disclosed as well as end products such as perfume extracts, toilet waters, cosmetic preparations, soaps, detergents and functional products, each of which also contains at least one of Products I-II.

REFERENCES:
patent: 3681395 (1972-08-01), Mookherjee et al.
patent: 4014902 (1977-03-01), Tseng
Magidson, Arch. Pharm. (Weinheim), Ges. 273,323 (1935).
J. Org. Chem. vol. 37, No. 24, pp. 3846-3848 (1972).

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