Substituted quinoline-2-carboxamides, their preparation and thei

Details Substituted quinoline-2-carboxamides, their preparation and thei Substituted quinoline-2-carboxamides, their preparation and thei

1996-07-03

1998-03-10

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21514, C07D21520

Patent

active

057263051

ABSTRACT:
The invention relates to substituted quinoline-2-carboxylic acid amides of the formula I ##STR1## their preparation and their use, and intermediates which are formed in the preparation of the compounds of the formula I. The compounds according to the invention are used as inhibitors of prolyl 4-hydroxylase and as pharmaceuticals (medicaments) for treatment of fibrotic diseases.

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