Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-06-30
1995-03-07
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483151, C07D40912, A61K 31415
Patent
active
053958470
ABSTRACT:
Angiotensin II receptor antagonists having tile formula: ##STR1## or a pharmaceutically acceptable salt thereof which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals. These antagonists function as prodrugs in vivo.
REFERENCES:
patent: 5185351 (1993-02-01), Finkelstein
Gaitanopoulos Dimitri E.
Weinstock Joseph
Gerstl Robert
Lentz Edward T.
McCarthy Mary E.
SmithKline Beecham Corporation
Venetianer Stephen
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