Methods for producing proteins which bind to predetermined antig

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 711, 43524027, 4353201, 4352523, 435 691, 536 2353, C07H 1900, C12P 2106, C12N 1500, C12N 120

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active

053957504

ABSTRACT:
Methods of producing a protein capable of binding to a predetermined antigen, screening libraries containing such proteins, and proteins and synthetic genes containing randomized sequences are disclosed.

REFERENCES:
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Huse et al., Science 246:1275-1281 (1989).
Clackson et al., Nature 352:624-628 (1991).
Dillon and Rosen, BioTechniques vol. 9, pp. 298 and 300 (1990).
Fuchs et al., Bio/Technology 9:1369-1372 (1991).
Barbas III et al., Proc. Natl. Acad. Sci. USA 88:7978-7982 (1991).
Winter and Milstein, Nature 349:293-299 (1991).
Bird et al., Science 243:423-426 (Oct. 31, 1988).

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