Process for producing antitumor compound

Details Process for producing antitumor compound Process for producing antitumor compound

1976-04-02

1977-03-08

Monacell, A. Louis

Textiles: fiber preparation

C12D 900

Patent

active

040111407

ABSTRACT:
A process for producing 5, 10, 11, 11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo-[2,1-C][1,4]benzod iazepin-2-acrylamide, which comprises aerobicatlly culturing Streptomyces spadicogriseus KOMATSU, FERM P-3275, ATCC 31179, belonging to the genus Streptomyces to produce said compound in the nutrient medium, and recovering said compound from the medium. The compound thus obtained has an excellent antitumor activity.

REFERENCES:
patent: 3361742 (1968-01-01), Berger et al.

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