Time-resolved fluorometer

Details Time-resolved fluorometer Time-resolved fluorometer

1989-01-31

1991-10-29

Evans, F. L.

Optics: measuring and testing

By shade or color

With color transmitting filter

2504581, 436528, 436529, 436517, 436805, 436172, 356318, G01N 2125, G01N 33544, F21V 916

Patent

active

050610767

ABSTRACT:
A time-resolved fluorometer, having a light tight enclosure, for detecting the presence of an analyte in a sample. Within the light tight enclosure are a pulsed dye laser that produces a pulsed light beam for sample excitation, a light tight sample excitation station through which samples, treated with a reagent composition, are passed into the path of the pulsed light excitation beam to produce a delayed fluorescence emission, a fused silica lens system through which the delayed fluorescence emission passes and an assembly which selectively amplifies, counts and characterizes the resulting emissions. The operation and coordination of the time resolved fluorometer are under computerized control as are the readings reported. Significant improvements relate to the fused silica lens systems and interference filters, cooling of the emission measurement apparatus and particularly the improved performance resulting from the combination of these aspects.

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Syvanen et al., Nucleic Acids Research 14:1017-1028.
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