Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-03-03
1998-06-23
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3147
Patent
active
057706050
ABSTRACT:
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumor activity and a high degree of safety, and can be applied as an antitumor medicine for curing tumors of various kinds.
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Mitsui et al Proc. Am. Assn for Cancer Res, vol. 34 p. 421 Mar. 1993.
Ejima Akio
Ohsuki Satoru
Terasawa Hirofumi
Uoto Kouichi
Daiichi Pharmaceutical Co. Ltd.
Daus Donald G.
Kabushiki Kaisha Yakul't Honsha
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