Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1994-05-09
1996-04-09
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
424439, 424441, 514 25, 514456, 514457, A61K 3170
Patent
active
055062113
ABSTRACT:
Disclosed are methods and compositions for use in inhibiting osteoclast activity and, particularly, the osteoclast acid secretion that leads to bone-degradation. It is shown that the isoflavone genistein inhibits the acid secretion of osteoclasts and reduces bone resorption. The present invention thus provides advantageous methods for use in inhibiting osteoclast activity, as may be employed to reduce bone loss, for example, in patients with osteoporosis, metastatic bone cancers and renal failure.
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Abstract from Japanese Patent, JP 5,170,756 (1993).
Barnes Stephen
Blair Harry C.
Dees Jos,e G.
Frazier Barbara S.
The UAB Research Foundation
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