Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1983-02-04
1985-02-12
Rollins, Alton D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514378, 548225, 548226, 548227, 548228, 548229, 548232, 548235, 548236, 548243, 548247, 548255, 548263, 548264, 548265, 548269, A61K 3141, A61K 3142, C07D24908, C07D26108
Patent
active
044991010
ABSTRACT:
The compounds are N,N'-substituted thioureas, ureas and guanidines which are H-2 histamine receptor inhibitors. Two compounds of this invention are N,N'-bis[2-((4-methyl-5-imidazolyl)methylthio)ethyl]thiourea and N,N'-bis[2-((4-methyl-5-imidazolyl)methylthio)ethyl]-N"-cyanoguanidine.
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Durant Graham J.
Ganellin Charon R.
Foggio Richard D.
Keps Joan S.
Lourie Alan D.
Rollins Alton D.
Smith Kline & French Laboratories Limited
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